CCL28

Across TCGA cell cohorts, CCL28 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCL28-associated genes across cancer lineages are PRSS54, SOX3, and NXNL1. Each is linked with CCL28 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL28-to-partner and partner-to-CCL28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS54 grouped by CCL28-low versus CCL28-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL28→partner) and Y-score (partner→CCL28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PRSS54 →	+0.035	+3.345	<.001	.007	3	1
LARGE_INTESTINE	SOX3 →	+0.035	+4.115	.008	.001	3	1
LARGE_INTESTINE	NXNL1 →	+0.097	+3.345	<.001	.007	3	1
LARGE_INTESTINE	GH1 →	+0.041	+3.345	.006	.007	3	1
LARGE_INTESTINE	SCYGR2 →	+0.043	+4.022	<.001	.006	3	1
LARGE_INTESTINE	HEATR9 →	+0.065	+3.502	.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

PRSS54 by CCL28 expression — LARGE_INTESTINE

Explore this box plot interactively →