Across TCGA patient cohorts, CCL27 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,200 significant associations in total. LGG shows the largest number of these associations.

The most reproducible CCL27-associated GO terms across cancer lineages are Regulation of chromatin organization, Obsolete histone modification, and Regulation of DNA recombination. Each is linked with CCL27 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCL27-to-partner and partner-to-CCL27 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL27→partner) and Y-score (partner→CCL27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Regulation of chromatin organization →	+0.098	+0.656	<.001	.001	3	4
SCLC	Obsolete histone modification →	+0.111	+0.808	<.001	<.001	3	3
LUAD	Regulation of DNA recombination →	+0.034	+0.005	<.001	.003	3	3
LUAD	Regulation of protein ubiquitination →	+0.031	+0.006	.001	.002	3	3
SCLC	Negative regulation of telomere maintenance →	+0.099	+0.614	.001	.001	3	3
LAML	Interleukin-11-mediated signaling pathway →	+0.076	+0.064	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,200 associations by consensus.

Exploration

CCL27 survival (RNA) · tumor vs normal (RNA) · all CCL27 data types