Across TCGA patient cohorts, CCL27 mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL27-associated genes across cancer lineages are RNA5SP369, RNA5SP182, and LINC00251. Each is linked with CCL27 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL27-to-partner and partner-to-CCL27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL27→partner) and Y-score (partner→CCL27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP369 →	+0.515	+3.778	.009	.007	3	2
UCEC	RNA5SP182 →	+1.137	+5.292	<.001	.002	3	2
UCEC	LINC00251 →	+0.163	+4.454	<.001	.002	3	2
BLCA	MIR3179-2 →	+0.408	+7.640	<.001	.009	3	1
BLCA	OR5B15P →	+0.094	+7.640	<.001	.009	3	1
SKCM	RNU7-159P →	+0.409	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Exploration

CCL27 survival (RNA) · tumor vs normal (RNA) · all CCL27 data types