CCL25

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CCL25 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CCL25 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher CCL25 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCL25 expression acts as an unfavorable survival marker.

ESCA are the cancer types where CCL25 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCADFSMedianII,III,IV0.0820.495.0026view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

CCL25–ESCA (DFS)

Kaplan–Meier survival curve for CCL25 mutant vs wild-type samples in ESCA.

Open the ESCA breakdown →

Exploration