Across TCGA pan-cancer cohorts, CCL25 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CCL25 data layer compared with 24 for mass-spec protein.
The strongest signal is observed in esophageal carcinoma (ESCA), where higher CCL25 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCL25 expression acts as an unfavorable survival marker.
ESCA are the cancer types where CCL25 Mutation most reproducibly stratifies survival.