CCL23

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CCL23 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CCL23 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in thyroid carcinoma (THCA), where higher CCL23 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCL23 expression acts as an unfavorable survival marker.

THCA and BRCA are the cancer types where CCL23 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCADFSMedianAll0.0270.945<.00124view →
BRCAOSMedianAll0.1120.578.01218view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CCL23–THCA (DFS)

Kaplan–Meier survival curve for CCL23 mutant vs wild-type samples in THCA.

Open the THCA breakdown →

Exploration