Across TCGA pan-cancer cohorts, CCL18 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CCL18 data layer compared with 25 for mass-spec protein and 6 for mass-spec protein.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher CCL18 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCL18 expression acts as an unfavorable survival marker.
LIHC are the cancer types where CCL18 Mutation most reproducibly stratifies survival.