CCL18

Across TCGA patient cohorts, CCL18 protein abundance is significantly associated with the RNA expression of many other genes, with 5,946 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCL18-associated genes across cancer lineages are FCGR2B, CD209, and LILRB5. Each is linked with CCL18 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCL18-to-partner and partner-to-CCL18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCL18 versus FCGR2B in GBM, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL18→partner) and Y-score (partner→CCL18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FCGR2B →	+1.114	+1.303	.003	<.001	3	8
BRCA	CD209 →	+0.946	+1.027	<.001	<.001	3	8
BRCA	LILRB5 →	+0.741	+0.861	<.001	<.001	3	7
LSCC	MS4A4A →	+0.799	+0.714	<.001	.001	3	7
GBM	MRC1 →	+1.518	+1.069	<.001	<.001	3	7
GBM	CR1 →	+1.034	+1.005	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,946 associations by consensus.

CCL18 vs FCGR2B — GBM

Explore this scatter interactively →