CCL18

Across TCGA cell cohorts, CCL18 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,142 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CCL18-associated GO terms across cancer lineages are Regulation of adaptive immune memory response, Artery smooth muscle contraction, and Synaptic vesicle maturation. Each is linked with CCL18 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCL18-to-partner and partner-to-CCL18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of adaptive immune memory response grouped by CCL18-low versus CCL18-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL18→partner) and Y-score (partner→CCL18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of adaptive immune memory response →	+0.225	+1.072	<.001	<.001	3	4
BLOOD_Leukemia	Artery smooth muscle contraction →	-0.961	-0.039	<.001	.003	3	3
SKIN	Synaptic vesicle maturation →	+0.094	+0.819	<.001	.001	3	3
SKIN	Secondary alcohol metabolic process →	+0.092	+0.985	<.001	<.001	3	3
SKIN	Positive regulation of microglial cell activation →	+1.561	+1.064	<.001	<.001	3	3
SKIN	Negative regulation of cytoplasmic translation →	+0.065	+0.729	.007	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,142 associations by consensus.

Regulation of adaptive immune memory response by CCL18 expression — SKIN

Explore this box plot interactively →