CCL17

Across TCGA patient cohorts, CCL17 mutation is significantly associated with the RNA expression of many other genes, with 107 significant associations in total. CESC shows the largest number of these associations.

The most reproducible CCL17-associated genes across cancer lineages are TRIM64EP, RNA5SP422, and RNU2-53P. Each is linked with CCL17 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL17-to-partner and partner-to-CCL17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM64EP grouped by CCL17-low versus CCL17-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL17→partner) and Y-score (partner→CCL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRIM64EP →	+0.075	+5.969	<.001	.002	3	2
UCEC	RNA5SP422 →	+1.405	+3.086	<.001	.007	3	2
SKCM	RNU2-53P →	+0.434	+7.816	<.001	.008	3	1
CESC	LYZL1 →	+0.056	+5.418	<.001	.005	3	1
CESC	TRIM51 →	+0.852	+5.010	<.001	.009	3	1
CESC	NPBWR2 →	+0.056	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 107 associations by consensus.

TRIM64EP by CCL17 expression — CESC

Explore this box plot interactively →