CCL16

Across TCGA patient cohorts, CCL16 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL16-associated genes across cancer lineages are ACC1, Cyclin-B1, and 14-3-3_beta. Each is linked with CCL16 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL16-to-partner and partner-to-CCL16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by CCL16-low versus CCL16-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL16→partner) and Y-score (partner→CCL16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.596	+2.820	.004	.035	3	1
UCEC	Cyclin-B1 →	+0.659	+3.000	.042	.037	2	1
UCEC	14-3-3_beta →	-0.139	-2.986	.016	.037	1	1
UCEC	p27_pT157 →	-0.069	-3.000	.039	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ACC1 by CCL16 expression — UCEC

Explore this box plot interactively →