CCL16

Across TCGA cell cohorts, CCL16 RNA expression is significantly associated with the go_rna of many other GO terms, with 117 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCL16-associated GO terms across cancer lineages are Regulation of mast cell activation, White fat cell proliferation, and Regulation of lipoprotein transport. Each is linked with CCL16 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL16-to-partner and partner-to-CCL16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mast cell activation grouped by CCL16-low versus CCL16-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL16→partner) and Y-score (partner→CCL16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of mast cell activation →	+0.108	+0.017	<.001	.004	3	2
LARGE_INTESTINE	White fat cell proliferation →	+0.789	+0.018	<.001	.002	3	2
LARGE_INTESTINE	Regulation of lipoprotein transport →	+0.114	+0.024	.003	.001	3	1
LARGE_INTESTINE	Positive regulation of lipoprotein transport →	+0.114	+0.024	.003	.001	3	1
LARGE_INTESTINE	Negative regulation of muscle hypertrophy →	+0.067	+0.022	.007	.007	3	1
LARGE_INTESTINE	Phospholipid transport →	+0.039	+0.017	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 117 associations by consensus.

Regulation of mast cell activation by CCL16 expression — LARGE_INTESTINE

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