CCL15

Across TCGA patient cohorts, CCL15 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL15-associated genes across cancer lineages are Rab25, VHL, and ATM. Each is linked with CCL15 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL15-to-partner and partner-to-CCL15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab25 grouped by CCL15-low versus CCL15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL15→partner) and Y-score (partner→CCL15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rab25 →	-0.534	-2.999	.003	.035	3	1
UCEC	VHL →	-1.166	-3.169	.001	.020	3	1
UCEC	ATM →	-0.507	-3.169	.041	.020	2	1
UCEC	Rictor_pT1135 →	-0.136	-3.169	.015	.020	1	1
UCEC	S6_pS240_S244 →	+0.502	+3.169	.024	.020	1	1
UCEC	ARID1A →	-0.227	-2.992	.030	.036	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Rab25 by CCL15 expression — UCEC

Explore this box plot interactively →