CCL14

Across TCGA patient cohorts, CCL14 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL14-associated genes across cancer lineages are ATM, Ku80, and Bax. Each is linked with CCL14 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL14-to-partner and partner-to-CCL14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by CCL14-low versus CCL14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL14→partner) and Y-score (partner→CCL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.647	-3.169	.009	.020	3	2
UCEC	Ku80 →	+0.285	+3.183	.028	.010	3	1
UCEC	Bax →	+0.301	+3.009	.022	.019	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.675	+2.817	.015	.036	2	1
UCEC	INPP4B →	-0.452	-3.000	.010	.036	2	1
UCEC	Di-Ras3 →	-0.200	-3.169	.014	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ATM by CCL14 expression — UCEC

Explore this box plot interactively →