CCL11

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCL11 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CCL11-associated genes across cancer lineages are OCM2, ZAN, and FATE1. Each is linked with CCL11 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL11-to-partner and partner-to-CCL11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OCM2 grouped by CCL11-low versus CCL11-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL11→partner) and Y-score (partner→CCL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADOCM2 →+0.028+4.078<.001.00931
LUNG_NSCLC_LUADZAN →+0.003+4.078<.001.00931
LUNG_NSCLC_LUADFATE1 →+0.058+4.093<.001.00431
LUNG_NSCLC_LUADFABP9 →+0.024+4.078<.001.00931
LUNG_NSCLC_LUADNLRP9 →+0.019+4.807<.001.00311
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OCM2 by CCL11 expression — LUNG_NSCLC_LUAD

Box plot of OCM2 in CCL11-low vs CCL11-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration