CCL1

Across TCGA patient cohorts, CCL1 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL1-associated genes across cancer lineages are eIF4E, GAPDH, and Ku80. Each is linked with CCL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL1-to-partner and partner-to-CCL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by CCL1-low versus CCL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL1→partner) and Y-score (partner→CCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.248	+3.000	.024	.036	3	1
UCEC	GAPDH →	+0.609	+3.000	.030	.036	3	1
UCEC	Ku80 →	+0.247	+2.820	.046	.035	3	1
UCEC	Caspase-8 →	-0.307	-2.973	.019	.035	3	1
UCEC	JNK2 →	+0.361	+3.321	<.001	.010	2	1
UCEC	STAT3_pY705 →	-0.613	-3.321	<.001	.010	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

eIF4E by CCL1 expression — UCEC

Explore this box plot interactively →