CCKBR

Across TCGA cell cohorts, CCKBR mutation is significantly associated with the RNA expression of many other genes, with 164 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCKBR-associated genes across cancer lineages are LILRA1, ASTN1, and CARTPT. Each is linked with CCKBR in more than 1 cancer types. Because this analysis shows association rather than direction, both CCKBR-to-partner and partner-to-CCKBR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LILRA1 grouped by CCKBR-low versus CCKBR-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCKBR→partner) and Y-score (partner→CCKBR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LILRA1 →	+0.023	+3.628	<.001	.002	3	1
LUNG_NSCLC_LUAD	ASTN1 →	+0.912	+3.605	<.001	.007	3	1
LUNG_NSCLC_LUAD	CARTPT →	+0.011	+4.266	<.001	.004	3	1
LUNG_NSCLC_LUAD	XAGE3 →	+0.106	+3.215	<.001	.007	3	1
LUNG_NSCLC_LUAD	PRR20B →	+0.019	+3.887	<.001	.002	3	1
LUNG_NSCLC_LUAD	PRR20A →	+0.019	+3.887	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 164 associations by consensus.

LILRA1 by CCKBR expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →