Across TCGA patient cohorts, CCIN mutation is significantly associated with the RNA expression of many other genes, with 2,614 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCIN-associated genes across cancer lineages are YBX1P9, RNU6ATAC42P, and MYPOP. Each is linked with CCIN in more than 2 cancer types. Because this analysis shows association rather than direction, both CCIN-to-partner and partner-to-CCIN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCIN→partner) and Y-score (partner→CCIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	YBX1P9 →	+0.081	+5.010	<.001	.009	3	3
CESC	RNU6ATAC42P →	+0.364	+5.103	.009	.008	3	2
SKCM	MYPOP →	+0.362	+3.510	.002	.002	3	2
SKCM	RNU6-1169P →	+0.146	+2.662	<.001	.005	3	2
SKCM	RNA5SP64 →	+0.099	+2.977	<.001	.007	3	2
SKCM	MTCO1P56 →	+0.066	+2.524	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,614 associations by consensus.

Exploration

CCIN survival (RNA) · tumor vs normal (RNA) · all CCIN data types