Across TCGA patient cohorts, CCHCR1 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCHCR1-associated genes across cancer lineages are ERK2, 14-3-3_beta, and EGFR_pY1068. Each is linked with CCHCR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCHCR1-to-partner and partner-to-CCHCR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCHCR1→partner) and Y-score (partner→CCHCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.178	+2.999	.021	.035	3	2
UCEC	14-3-3_beta →	-0.111	-3.143	.006	.018	3	1
UCEC	EGFR_pY1068 →	-0.262	-1.906	.009	.016	3	1
UCEC	INPP4B →	-0.289	-2.000	.026	.030	3	1
UCEC	MEK1 →	+0.388	+1.906	.008	.016	3	1
UCEC	MSH6 →	-0.335	-1.990	.011	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

CCHCR1 survival (RNA) · tumor vs normal (RNA) · all CCHCR1 data types