Across TCGA cell cohorts, CCHCR1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCHCR1-associated genes across cancer lineages are GSTA5, DEFA4, and ADAM7. Each is linked with CCHCR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCHCR1-to-partner and partner-to-CCHCR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCHCR1→partner) and Y-score (partner→CCHCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	GSTA5 →	+0.031	+3.981	<.001	.001	3	1
LARGE_INTESTINE	DEFA4 →	+0.026	+4.022	<.001	.006	3	1
LARGE_INTESTINE	ADAM7 →	+0.004	+3.345	<.001	.007	3	1
BLOOD_Leukemia	TAS2R7 →	+0.016	+4.507	<.001	.001	3	1
BLOOD_Leukemia	CST8 →	+0.041	+4.384	<.001	.006	3	1
BLOOD_Leukemia	SMIM32 →	+0.019	+4.169	.009	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

CCHCR1 survival (RNA) · tumor vs normal (RNA) · all CCHCR1 data types