CCER2

Across TCGA pan-cancer cohorts, CCER2 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated CCER2 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CCER2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCER2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SCLC show a favorable association.

ACC, KIRC, and HNSC are the cancer types where CCER2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.392	0.756	<.001	92	view →
KIRC	DFS	Median	All	0.534	0.697	<.001	85	view →
HNSC	OS	Median	III,IV	0.522	0.205	.001	68	view →
SCLC	DFS	Quartile	III,IV	0.912	0.347	.001	56	view →
LGG	DFS	Median	All	0.618	0.844	<.001	48	view →
BLCA	OS	Quartile	II,III,IV	0.784	0.666	.010	46	view →
PAAD	DFS	Median	All	0.471	0.242	.008	26	view →
MESO	DFS	Tertile	III,IV	0.291	0.505	.010	24	view →
UCEC	OS	Quartile	II,III,IV	0.300	0.782	.021	24	view →
UCS	DFS	Quartile	III,IV	0.584	0.169	.024	24	view →
COAD	OS	Median	II,III,IV	0.810	0.892	.007	22	view →
PRAD	DFS	Median	All	0.684	0.887	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

CCER2–ACC (DFS)

Open the ACC breakdown →