CCDC97

Across TCGA pan-cancer cohorts, CCDC97 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CCDC97 data layer compared with 28 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CCDC97 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC97 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

PDAC, CCRCC, and HNSC are the cancer types where CCDC97 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	III,IV	0.367	0.853	.003	29	view →
CCRCC	DFS	Tertile	III,IV	0.981	0.042	.024	6	view →
HNSC	DFS	Median	All	0.698	1.000	.020	6	view →
LSCC	DFS	Quartile	All	0.688	0.909	.015	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CCDC97–PDAC (OS)

Open the PDAC breakdown →