CCDC97

Across TCGA patient cohorts, CCDC97 mutation is significantly associated with the RNA expression of many other genes, with 802 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC97-associated genes across cancer lineages are RNA5SP415, HMX2, and TRAJ9. Each is linked with CCDC97 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC97-to-partner and partner-to-CCDC97 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP415 grouped by CCDC97-low versus CCDC97-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC97→partner) and Y-score (partner→CCDC97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP415 →	+0.238	+7.640	<.001	.009	3	2
UCEC	HMX2 →	+0.761	+2.360	.001	.005	3	2
UCEC	TRAJ9 →	+0.496	+2.144	.003	.001	3	2
UCEC	MTATP6P21 →	+0.395	+2.815	<.001	<.001	3	2
SKCM	HNRNPA1P3 →	+0.083	+3.287	.001	.008	3	2
SKCM	MIR3689F →	+0.290	+4.469	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 802 associations by consensus.

RNA5SP415 by CCDC97 expression — BLCA

Explore this box plot interactively →