CCDC97

Across TCGA patient cohorts, CCDC97 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC97-associated genes across cancer lineages are ATM, eEF2, and Lck. Each is linked with CCDC97 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC97-to-partner and partner-to-CCDC97 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by CCDC97-low versus CCDC97-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC97→partner) and Y-score (partner→CCDC97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.509	-2.308	.010	.033	3	2
UCEC	eEF2 →	+0.375	+2.999	.016	.035	3	1
UCEC	Lck →	+0.217	+2.807	.013	.003	3	1
UCEC	MEK1 →	+0.392	+2.115	.014	.019	3	1
UCEC	p62 Lck ligand →	+0.309	+2.115	.030	.019	3	1
UCEC	STAT3_pY705 →	-0.269	-2.321	.018	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ATM by CCDC97 expression — UCEC

Explore this box plot interactively →