CCDC93

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC93 mutation is significantly associated with the RNA expression of many other genes, with 2,800 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC93-associated genes across cancer lineages are OR9Q2, HMGN2P16, and PAICSP6. Each is linked with CCDC93 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC93-to-partner and partner-to-CCDC93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9Q2 grouped by CCDC93-low versus CCDC93-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC93→partner) and Y-score (partner→CCDC93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADOR9Q2 →+0.025+4.498.002<.00134
SARCHMGN2P16 →+0.211+5.620<.001.00433
LUSCPAICSP6 →+0.027+4.038<.001.00333
UCECCDCA2 →+0.756+2.678<.001<.00133
UCECC12orf65 →+0.334+2.111<.001.00333
UCECSCO1 →+0.509+3.917<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,800 associations by consensus.

OR9Q2 by CCDC93 expression — COAD

Box plot of OR9Q2 in CCDC93-low vs CCDC93-high samples in COAD.

Explore this box plot interactively →

Exploration