CCDC93

Across TCGA patient cohorts, CCDC93 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC93-associated genes across cancer lineages are INPP4B, ATM, and Mre11. Each is linked with CCDC93 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC93-to-partner and partner-to-CCDC93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by CCDC93-low versus CCDC93-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC93→partner) and Y-score (partner→CCDC93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.536	-3.169	.003	.018	3	2
COAD	ATM →	-0.660	-3.000	<.001	.035	2	3
UCEC	Mre11 →	-0.064	-1.440	.031	.024	3	2
UCEC	Rad50 →	-0.191	-1.440	.022	.024	3	2
UCEC	RBM15 →	+0.249	+2.115	.024	.017	3	2
UCEC	ASNS →	+0.361	+1.736	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

INPP4B by CCDC93 expression — COAD

Explore this box plot interactively →