CCDC93

Across TCGA cell cohorts, CCDC93 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CCDC93-associated genes across cancer lineages are CCL19, KRTAP21-1, and PRAMEF17. Each is linked with CCDC93 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC93-to-partner and partner-to-CCDC93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL19 grouped by CCDC93-low versus CCDC93-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC93→partner) and Y-score (partner→CCDC93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CCL19 →	+0.065	+4.415	<.001	.007	3	1
SKIN	KRTAP21-1 →	+0.037	+5.022	<.001	.002	3	1
SKIN	PRAMEF17 →	+0.012	+5.022	<.001	.002	3	1
LARGE_INTESTINE	CD207 →	+0.240	+3.862	<.001	.005	3	1
LARGE_INTESTINE	KCTD8 →	+0.238	+3.510	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CCL19 by CCDC93 expression — SKIN

Explore this box plot interactively →