CCDC92

Across TCGA patient cohorts, CCDC92 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC92-associated genes across cancer lineages are INPP4B, PCNA, and AMPK_alpha. Each is linked with CCDC92 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC92-to-partner and partner-to-CCDC92 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by CCDC92-low versus CCDC92-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC92→partner) and Y-score (partner→CCDC92) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.402	-3.161	.029	.019	3	1
COAD	PCNA →	+0.269	+3.178	.027	.010	3	1
COAD	AMPK_alpha →	-0.194	-3.127	.029	.019	3	1
COAD	Rictor →	-1.187	-3.161	.016	.019	3	1
COAD	Axl →	-0.301	-2.981	.031	.036	3	1
UCEC	JNK2 →	+0.249	+2.906	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

INPP4B by CCDC92 expression — COAD

Explore this box plot interactively →