CCDC91

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC91 mutation is significantly associated with the RNA expression of many other genes, with 990 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC91-associated genes across cancer lineages are UBL5P1, MIR6856, and WRBP1. Each is linked with CCDC91 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC91-to-partner and partner-to-CCDC91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBL5P1 grouped by CCDC91-low versus CCDC91-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC91→partner) and Y-score (partner→CCDC91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADUBL5P1 →+0.273+4.283<.001.00133
SKCMMIR6856 →+0.268+3.186<.001.00932
SKCMWRBP1 →+0.227+3.367<.001.00232
UCECNKAP →+0.417+3.818.005<.00132
UCECCDADC1 →+0.508+2.732<.001.00332
UCECKCTD9 →+0.713+3.354.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 990 associations by consensus.

UBL5P1 by CCDC91 expression — COAD

Box plot of UBL5P1 in CCDC91-low vs CCDC91-high samples in COAD.

Explore this box plot interactively →

Exploration