CCDC91

Across TCGA patient cohorts, CCDC91 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC91-associated genes across cancer lineages are TFRC, EGFR_pY1068, and JNK2. Each is linked with CCDC91 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC91-to-partner and partner-to-CCDC91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by CCDC91-low versus CCDC91-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC91→partner) and Y-score (partner→CCDC91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.670	+2.321	.011	.035	3	2
UCEC	EGFR_pY1068 →	-0.333	-2.321	.008	.035	3	1
UCEC	JNK2 →	+0.226	+3.009	.024	.019	3	1
UCEC	MAPK_pT202_Y204 →	-0.703	-3.169	.002	.019	3	1
UCEC	MEK1_p_S217_S221 →	-0.359	-2.321	.008	.035	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.727	-3.321	.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

TFRC by CCDC91 expression — UCEC

Explore this box plot interactively →