CCDC90B

Across TCGA pan-cancer cohorts, CCDC90B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CCDC90B data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CCDC90B mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC90B expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

LUAD, CCRCC, and PDAC are the cancer types where CCDC90B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	II,III,IV	0.451	0.861	.002	32	view →
CCRCC	DFS	Median	All	0.633	0.866	.008	14	view →
PDAC	OS	Median	III,IV	0.325	0.543	.026	11	view →
HNSC	DFS	Median	III,IV	0.725	0.508	.017	7	view →
LSCC	OS	Median	All	1.000	0.924	.013	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CCDC90B–LUAD (OS)

Open the LUAD breakdown →