CCDC90B

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC90B mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC90B-associated genes across cancer lineages are Tuberin and P-Cadherin. Each is linked with CCDC90B in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC90B-to-partner and partner-to-CCDC90B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tuberin grouped by CCDC90B-low versus CCDC90B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC90B→partner) and Y-score (partner→CCDC90B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTuberin →+0.392+3.169.008.02021
UCECP-Cadherin →-0.178-3.156.024.02011
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Tuberin by CCDC90B expression — UCEC

Box plot of Tuberin in CCDC90B-low vs CCDC90B-high samples in UCEC.

Explore this box plot interactively →

Exploration