CCDC90B

Across TCGA cell cohorts, CCDC90B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,794 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC90B-associated GO terms across cancer lineages are Positive regulation of protein K48-linked ubiquitination, Regulation of protein monoubiquitination, and Positive regulation of protein monoubiquitination. Each is linked with CCDC90B in more than 13 cancer types. Because this analysis shows association rather than direction, both CCDC90B-to-partner and partner-to-CCDC90B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein K48-linked ubiquitination grouped by CCDC90B-low versus CCDC90B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC90B→partner) and Y-score (partner→CCDC90B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of protein K48-linked ubiquitination →	+0.133	+0.772	.002	.003	2	14
LUNG_NSCLC_LUSC	Regulation of protein monoubiquitination →	+0.168	+0.868	<.001	.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of protein monoubiquitination →	+0.168	+0.868	<.001	.001	3	12
URINARY_TRACT	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.137	+0.533	.002	.002	3	9
URINARY_TRACT	DAMP biosynthetic process →	+0.137	+0.533	.002	.002	3	9
LIVER	Formaldehyde catabolic process →	+0.123	+0.750	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,794 associations by consensus.

Positive regulation of protein K48-linked ubiquitination by CCDC90B expression — URINARY_TRACT

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