CCDC9

Across TCGA patient cohorts, CCDC9 mutation is significantly associated with the RNA expression of many other genes, with 1,271 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC9-associated genes across cancer lineages are GAGE12H, SNRNP25, and GFI1. Each is linked with CCDC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC9-to-partner and partner-to-CCDC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE12H grouped by CCDC9-low versus CCDC9-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC9→partner) and Y-score (partner→CCDC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	GAGE12H →	+0.301	+5.305	<.001	.003	3	2
UCEC	SNRNP25 →	+0.407	+2.577	.006	<.001	3	2
UCEC	GFI1 →	+0.457	+2.831	.003	.001	3	2
UCEC	CRK →	+0.381	+2.523	.005	.001	3	2
UCEC	CHAF1A →	+0.527	+2.502	.004	.009	3	2
UCEC	TIMM22 →	+0.401	+2.913	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,271 associations by consensus.

GAGE12H by CCDC9 expression — LIHC

Explore this box plot interactively →