CCDC89

Across TCGA patient cohorts, CCDC89 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,130 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CCDC89-associated proteins across cancer lineages are BBS2, RPL5, and BBS7. Each is linked with CCDC89 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCDC89-to-partner and partner-to-CCDC89 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC89 versus BBS2 in UCEC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC89→partner) and Y-score (partner→CCDC89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BBS2 →	+0.424	+0.774	<.001	<.001	3	7
BRCA	RPL5 →	-0.221	-0.577	<.001	<.001	3	6
LSCC	BBS7 →	+0.406	+0.660	<.001	<.001	3	6
PDAC	PEA15 →	+0.628	+0.425	<.001	<.001	3	5
LSCC	PRKG1 →	+0.511	+0.524	<.001	<.001	3	5
LSCC	RAI14 →	+0.344	+0.557	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,130 associations by consensus.

CCDC89 vs BBS2 — UCEC

Explore this scatter interactively →