CCDC89

Across TCGA cell cohorts, CCDC89 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,050 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CCDC89-associated GO terms across cancer lineages are Regulation of DNA-templated transcription initiation, Negative regulation of autophagy, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with CCDC89 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCDC89-to-partner and partner-to-CCDC89 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA-templated transcription initiation grouped by CCDC89-low versus CCDC89-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC89→partner) and Y-score (partner→CCDC89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of DNA-templated transcription initiation →	+0.063	+1.226	<.001	<.001	3	8
OVARY	Negative regulation of autophagy →	+0.053	+1.104	<.001	<.001	3	7
OVARY	Mitochondrial electron transport, cytochrome c to oxygen →	+0.078	+0.850	<.001	.004	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of intracellular transport →	+0.057	+0.471	.002	.008	3	7
STOMACH	Protein-containing complex disassembly →	+0.093	+1.077	<.001	<.001	3	7
SOFT_TISSUE	Regulation of transcription initiation by RNA polymerase II →	+0.059	+0.931	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,050 associations by consensus.

Regulation of DNA-templated transcription initiation by CCDC89 expression — SOFT_TISSUE

Explore this box plot interactively →