CCDC89

Across TCGA cell cohorts, CCDC89 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC89-associated genes across cancer lineages are MMP27 and KRTAP12-3. Each is linked with CCDC89 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC89-to-partner and partner-to-CCDC89 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP27 grouped by CCDC89-low versus CCDC89-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC89→partner) and Y-score (partner→CCDC89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MMP27 →	+0.026	+5.969	<.001	.001	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.082	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MMP27 by CCDC89 expression — BLOOD_Leukemia

Explore this box plot interactively →