CCDC88A

Across TCGA patient cohorts, CCDC88A protein abundance is significantly associated with the RNA expression of many other genes, with 15,048 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC88A-associated genes across cancer lineages are BTK, PLEK, and TYROBP. Each is linked with CCDC88A in more than 7 cancer types. Because this analysis shows association rather than direction, both CCDC88A-to-partner and partner-to-CCDC88A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC88A versus BTK in UCEC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC88A→partner) and Y-score (partner→CCDC88A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BTK →	+1.109	+0.397	<.001	<.001	3	8
UCEC	PLEK →	+1.209	+0.323	<.001	.002	3	8
UCEC	TYROBP →	+1.095	+0.400	<.001	<.001	3	8
UCEC	NCKAP1L →	+1.045	+0.410	<.001	<.001	3	8
HNSC	EMP3 →	+1.030	+0.273	<.001	<.001	3	8
UCEC	FCER1G →	+0.971	+0.335	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,048 associations by consensus.

CCDC88A vs BTK — UCEC

Explore this scatter interactively →