CCDC88A

Across TCGA patient cohorts, CCDC88A mutation is significantly associated with the RNA expression of many other genes, with 6,604 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC88A-associated genes across cancer lineages are POC1A, SEC13, and SMIM4. Each is linked with CCDC88A in more than 4 cancer types. Because this analysis shows association rather than direction, both CCDC88A-to-partner and partner-to-CCDC88A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POC1A grouped by CCDC88A-low versus CCDC88A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC88A→partner) and Y-score (partner→CCDC88A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POC1A →	+0.447	+2.700	<.001	<.001	3	5
UCEC	SEC13 →	+0.390	+1.823	<.001	<.001	3	4
UCEC	SMIM4 →	+0.404	+1.595	<.001	<.001	3	4
UCEC	TOMM5 →	+0.310	+1.617	.002	<.001	3	4
UCEC	POLE →	+0.417	+1.347	<.001	<.001	3	4
UCEC	TIPIN →	+0.520	+2.146	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,604 associations by consensus.

POC1A by CCDC88A expression — UCEC

Explore this box plot interactively →