CCDC88A

Across TCGA patient cohorts, CCDC88A mutation is significantly associated with the total protein of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC88A-associated genes across cancer lineages are PDCD4, RAD51, and Cyclin-B1. Each is linked with CCDC88A in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC88A-to-partner and partner-to-CCDC88A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by CCDC88A-low versus CCDC88A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC88A→partner) and Y-score (partner→CCDC88A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.318	-0.830	.008	.049	3	4
COAD	RAD51 →	+0.204	+2.330	.003	.020	3	3
COAD	Cyclin-B1 →	+0.542	+3.467	.027	.002	3	3
UCEC	GAPDH →	+0.303	+1.064	.028	.043	3	3
UCEC	ATM →	-0.495	-2.794	<.001	<.001	3	3
BLCA	AMPK_alpha →	-0.130	-2.000	.026	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

PDCD4 by CCDC88A expression — UCEC

Explore this box plot interactively →