CCDC88A

Across TCGA cell cohorts, CCDC88A mutation is significantly associated with the RNA expression of many other genes, with 656 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC88A-associated genes across cancer lineages are FMO1, NOA1, and SLC38A8. Each is linked with CCDC88A in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC88A-to-partner and partner-to-CCDC88A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FMO1 grouped by CCDC88A-low versus CCDC88A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC88A→partner) and Y-score (partner→CCDC88A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FMO1 →	+0.077	+2.015	.001	.005	3	2
LARGE_INTESTINE	NOA1 →	+0.570	+3.628	<.001	<.001	3	2
BLOOD_Lymphoma	SLC38A8 →	+0.109	+4.191	<.001	.007	3	1
LUNG_NSCLC_LUAD	GH2 →	+0.037	+2.959	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR1N1 →	+0.019	+3.149	.002	.002	3	1
LUNG_NSCLC_LUAD	FOXR1 →	+0.073	+2.958	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 656 associations by consensus.

FMO1 by CCDC88A expression — LARGE_INTESTINE

Explore this box plot interactively →