Across TCGA cell cohorts, CCDC85C mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC85C-associated genes across cancer lineages are TEX50, PRAMEF20, and KRTAP10-2. Each is linked with CCDC85C in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC85C-to-partner and partner-to-CCDC85C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC85C→partner) and Y-score (partner→CCDC85C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TEX50 →	+0.026	+5.977	<.001	.001	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	KRTAP10-2 →	+0.054	+3.994	<.001	.002	3	1
LARGE_INTESTINE	MS4A18 →	+0.022	+3.510	<.001	.003	3	1
LARGE_INTESTINE	ADAM7 →	+0.004	+3.345	<.001	.007	3	1
LUNG_NSCLC_LUAD	PTH →	+0.031	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

CCDC85C survival (RNA) · tumor vs normal (RNA) · all CCDC85C data types