CCDC82

Across TCGA pan-cancer cohorts, CCDC82 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CCDC82 data layer compared with 21 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CCDC82 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CCDC82 expression acts as an unfavorable survival marker, although some lineages such as HNSC and GBM show a favorable association.

HNSC, GBM, and CCRCC are the cancer types where CCDC82 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	II,III,IV	0.924	0.414	.001	35	view →
GBM	OS	Median	All	0.660	0.393	<.001	29	view →
CCRCC	DFS	Quartile	All	1.000	0.347	.005	18	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.328	.002	15	view →
LSCC	OS	Median	All	0.882	0.742	.020	5	view →
PDAC	OS	Median	All	0.810	0.926	.021	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CCDC82–HNSC (DFS)

Open the HNSC breakdown →