CCDC82

Across TCGA patient cohorts, CCDC82 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC82-associated genes across cancer lineages are p27_pT198, ATM, and eIF4E. Each is linked with CCDC82 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC82-to-partner and partner-to-CCDC82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p27_pT198 grouped by CCDC82-low versus CCDC82-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC82→partner) and Y-score (partner→CCDC82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT198 →	+0.079	+1.678	.027	.021	3	3
UCEC	ATM →	-0.504	-1.874	<.001	.002	3	3
UCEC	eIF4E →	+0.207	+3.472	.003	.002	3	2
UCEC	Notch1 →	+0.100	+1.321	.033	.029	3	2
UCEC	p62 Lck ligand →	+0.381	+2.201	<.001	<.001	3	2
UCEC	p90 RSK →	+0.127	+1.495	.047	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

p27_pT198 by CCDC82 expression — UCEC

Explore this box plot interactively →