CCDC82

Across TCGA cell cohorts, CCDC82 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,715 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CCDC82-associated GO terms across cancer lineages are Positive regulation of protein K48-linked ubiquitination, Microtubule organizing center organization, and Centrosome cycle. Each is linked with CCDC82 in more than 16 cancer types. Because this analysis shows association rather than direction, both CCDC82-to-partner and partner-to-CCDC82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein K48-linked ubiquitination grouped by CCDC82-low versus CCDC82-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC82→partner) and Y-score (partner→CCDC82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of protein K48-linked ubiquitination →	+0.124	+2.393	<.001	<.001	3	17
BLOOD_Lymphoma	Microtubule organizing center organization →	+0.073	+1.050	<.001	<.001	3	16
BREAST	Centrosome cycle →	+0.078	+2.615	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Negative regulation of metaphase/anaphase transition of cell cycle →	+0.141	+1.471	.009	<.001	3	15
LUNG_NSCLC_LUSC	Negative regulation of chromosome separation →	+0.141	+1.471	.009	<.001	3	15
URINARY_TRACT	Centrosome duplication →	+0.089	+1.075	.005	.003	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,715 associations by consensus.

Positive regulation of protein K48-linked ubiquitination by CCDC82 expression — BREAST

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