CCDC80

Across TCGA pan-cancer cohorts, CCDC80 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CCDC80 data layer compared with 23 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CCDC80 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC80 expression acts as an unfavorable survival marker.

CCRCC, PDAC, and LSCC are the cancer types where CCDC80 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.105	0.928	.003	40	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	25	view →
LSCC	OS	Quartile	All	0.751	0.967	.003	22	view →
LUAD	OS	Median	All	0.767	0.902	.006	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CCDC80–CCRCC (DFS)

Open the CCRCC breakdown →