CCDC80

Across TCGA cell cohorts, CCDC80 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,415 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCDC80-associated GO terms across cancer lineages are Protein activation cascade, Blood coagulation, fibrin clot formation, and Regulation of intracellular transport. Each is linked with CCDC80 in more than 14 cancer types. Because this analysis shows association rather than direction, both CCDC80-to-partner and partner-to-CCDC80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein activation cascade grouped by CCDC80-low versus CCDC80-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC80→partner) and Y-score (partner→CCDC80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Protein activation cascade →	+0.447	+6.222	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Blood coagulation, fibrin clot formation →	+0.402	+4.852	.001	<.001	3	15
STOMACH	Regulation of intracellular transport →	+0.078	+4.405	<.001	<.001	3	15
STOMACH	Regulation of intracellular protein transport →	+0.078	+3.109	.001	.005	3	15
LIVER	Regulation of fibroblast proliferation →	+0.110	+3.865	.002	.006	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular protein transport →	+0.078	+1.805	.001	.004	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,415 associations by consensus.

Protein activation cascade by CCDC80 expression — LUNG_NSCLC_LUSC

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