CCDC78

Across TCGA patient cohorts, CCDC78 protein abundance is significantly associated with the RNA expression of many other genes, with 3,194 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC78-associated genes across cancer lineages are SPEF1, RSPH4A, and PACRG. Each is linked with CCDC78 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC78-to-partner and partner-to-CCDC78 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC78 versus SPEF1 in UCEC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC78→partner) and Y-score (partner→CCDC78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPEF1 →	+1.791	+0.719	<.001	<.001	3	3
UCEC	RSPH4A →	+1.961	+0.842	<.001	<.001	3	3
UCEC	PACRG →	+1.183	+0.717	<.001	<.001	3	3
UCEC	C6orf118 →	+2.292	+0.910	<.001	<.001	3	3
LSCC	DNAH6 →	+1.405	+1.088	<.001	<.001	3	3
UCEC	ADGB →	+1.748	+0.732	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,194 associations by consensus.

CCDC78 vs SPEF1 — UCEC

Explore this scatter interactively →