CCDC78

Across TCGA cell cohorts, CCDC78 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,271 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CCDC78-associated GO terms across cancer lineages are De novo centriole assembly involved in multi-ciliated epithelial cell differentiation, De novo centriole assembly, and Multi-ciliated epithelial cell differentiation. Each is linked with CCDC78 in more than 13 cancer types. Because this analysis shows association rather than direction, both CCDC78-to-partner and partner-to-CCDC78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, De novo centriole assembly involved in multi-ciliated epithelial cell differentiation grouped by CCDC78-low versus CCDC78-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC78→partner) and Y-score (partner→CCDC78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	De novo centriole assembly involved in multi-ciliated epithelial cell differentiation →	+0.203	+1.362	<.001	.001	3	14
BLOOD_Myeloma	De novo centriole assembly →	+0.209	+1.362	<.001	.001	3	13
BLOOD_Myeloma	Multi-ciliated epithelial cell differentiation →	+0.198	+1.411	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Pre-mRNA catabolic process →	+0.177	+1.489	<.001	<.001	3	12
LARGE_INTESTINE	Calcium-independent cell-matrix adhesion →	+0.165	+0.926	<.001	.001	3	12
STOMACH	Positive regulation of ceramide biosynthetic process →	+0.160	+1.474	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,271 associations by consensus.

De novo centriole assembly involved in multi-ciliated epithelial cell differentiation by CCDC78 expression — BLOOD_Myeloma

Explore this box plot interactively →