CCDC77

Across TCGA cell cohorts, CCDC77 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,012 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC77-associated GO terms across cancer lineages are Nuclear division, Chromosome segregation, and Chromosome condensation. Each is linked with CCDC77 in more than 19 cancer types. Because this analysis shows association rather than direction, both CCDC77-to-partner and partner-to-CCDC77 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear division grouped by CCDC77-low versus CCDC77-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC77→partner) and Y-score (partner→CCDC77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear division →	+0.093	+0.974	.002	.005	3	20
OESOPHAGUS	Chromosome segregation →	+0.148	+1.127	.002	.004	3	20
BREAST	Chromosome condensation →	+0.170	+1.165	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome →	+0.111	+0.899	.002	<.001	3	19
BONE	Regulation of centrosome cycle →	+0.074	+0.908	<.001	<.001	3	19
BLOOD_Myeloma	DNA replication →	+0.131	+1.257	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,012 associations by consensus.

Nuclear division by CCDC77 expression — BONE

Explore this box plot interactively →