CCDC77

Across TCGA cell cohorts, CCDC77 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CCDC77-associated genes across cancer lineages are AMY1A, CABP5, and AGTR2. Each is linked with CCDC77 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC77-to-partner and partner-to-CCDC77 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMY1A grouped by CCDC77-low versus CCDC77-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC77→partner) and Y-score (partner→CCDC77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AMY1A →	+0.167	+3.977	<.001	.001	3	1
BLOOD_Lymphoma	CABP5 →	+0.016	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	AGTR2 →	+0.023	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	OR5P2 →	+0.028	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	C18orf63 →	+0.012	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

AMY1A by CCDC77 expression — LARGE_INTESTINE

Explore this box plot interactively →